Pharmacophore modeling and 3D-QSAR study for the design of novel α-synuclein aggregation inhibitors
Jixia Yang, Jiajing Hu, Gongzheng Zhang, Qin Li, Hongliang Wen, Yun Tang
Topics & Concepts
PharmacophoreQuantitative structure–activity relationshipChemistrySynucleinopathiesLigand (biochemistry)StereochemistryVirtual screeningComputational biologyParkinson's diseaseAlpha-synucleinBiochemistryBiologyReceptorDiseasePathologyMedicineParkinson's Disease Mechanisms and TreatmentsBiochemical and biochemical processesCholinesterase and Neurodegenerative Diseases