A multifunctional non-viral vector for the delivery of MTH1-targeted CRISPR/Cas9 system for non-small cell lung cancer therapy
Yu Wang, Yan Tang, Xiaomei Zhao, Gui Huang, Jinhong Gong, Shu-di Yang, Hui Li, Wenjun Wan, Changhao Jia, Gang Chen, Xuenong Zhang
Topics & Concepts
CRISPRCas9BiologyGenetic enhancementViral vectorGenome editingGene deliveryPlasmidCancer researchNucleaseComputational biologyGeneGeneticsRecombinant DNACRISPR and Genetic EngineeringVirus-based gene therapy researchRNA Interference and Gene Delivery