Small molecule modulation of the p75 neurotrophin receptor suppresses age- and genotype-associated neurodegeneration in HIV gp120 transgenic mice
Youmie Xie, Jaimie A. Seawell, Emily Boesch, Lauren D. Allen, Ashley Suchy, Frank M. Longo, Rick B. Meeker
Topics & Concepts
NeurotrophinNeuroprotectionNeurodegenerationMicrogliaBiologyNeuroscienceReceptorNeurotrophin-3HippocampusTau proteinInflammationEndocrinologyGenetically modified mouseInternal medicineCell biologyImmunologyTransgeneNeurotrophic factorsAlzheimer's diseaseMedicineBrain-derived neurotrophic factorDiseaseGeneticsGeneNerve injury and regenerationNeuroinflammation and Neurodegeneration MechanismsHIV Research and Treatment