From imines to amides <i>via</i> NHC-mediated oxidation
Shaofa Sun, Donghui Guo, Fangyi Li, Jian Wang
Abstract
An efficient construction of amides through NHC-mediated oxidation of imines is described. This work has the advantages of wide scope, fast assembly and high yield, and can avoid the use of coupling agents, such as HATU, DCC, etc.
Topics & Concepts
ChemistryScope (computer science)Yield (engineering)Combinatorial chemistryOrganic chemistryComputer scienceProgramming languageMetallurgyMaterials scienceN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsSynthetic Organic Chemistry Methods