A perspective on <i>C. elegans</i> neurodevelopment: from early visionaries to a booming neuroscience research
Georgia Rapti
Abstract
neurodevelopment, from the generation and diversification of neural components to their navigation and connectivity. I point out recent noteworthy findings in the fields of glia biology, sex dimorphism and plasticity in neurodevelopment, highlighting how current research connects back to the pioneering studies by Brenner, Sulston and colleagues. Multifaceted investigations in model organisms, connecting genes to cell function and behavior, expand our mechanistic understanding of neurodevelopment while allowing us to formulate emerging questions for future discoveries.
Topics & Concepts
NeuroscienceCaenorhabditis elegansBiologyConnectomeModel organismPerspective (graphical)Lineage (genetic)Function (biology)Cognitive scienceNeuroplasticityGenomeEvolutionary biologyGenePsychologyGeneticsComputer scienceFunctional connectivityArtificial intelligenceGenetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatoninSpaceflight effects on biology