Downregulation of the zinc transporter SLC39A13 (ZIP13) is responsible for the activation of CaMKII at reperfusion and leads to myocardial ischemia/reperfusion injury in mouse hearts
Jie Wang, Xinxin Cheng, Huanhuan Zhao, Qing Yang, Zhelong Xu
Topics & Concepts
Downregulation and upregulationKnockout mousePhosphorylationCell biologyReperfusion injuryMitochondrionChemistryIschemiaInternal medicineBiologyMedicineBiochemistryReceptorGeneTrace Elements in HealthViral Infections and Immunology ResearchCardiac electrophysiology and arrhythmias