GDF11 ameliorates severe acute pancreatitis through modulating macrophage M1 and M2 polarization by targeting the TGFβR1/SMAD-2 pathway
Feixiang Duan, Xiaowu Wang, Hongwei Wang, Yongqiang Wang, Yan Zhang, Jiawei Chen, Xiandong Zhu, Bicheng Chen
Topics & Concepts
Macrophage polarizationInflammationIn vivoSMADTransforming growth factorPathogenesisM2 MacrophageMacrophageCancer researchBiologyCell biologyIn vitroImmunologyBiochemistryBiotechnologyPancreatitis Pathology and TreatmentPancreatic and Hepatic Oncology ResearchPhagocytosis and Immune Regulation