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Transient nuclear deformation primes epigenetic state and promotes cell reprogramming

Yang Song, Jennifer Soto, Binru Chen, Tyler Hoffman, Weikang Zhao, Ninghao Zhu, Peng Qin, Longwei Liu, Chau Ly, Pak Kin Wong, Yingxiao Wang, Amy C. Rowat, Siavash K. Kurdistani, Song Li

2022Nature Materials115 citationsDOIOpen Access PDF

Topics & Concepts

ReprogrammingCell biologyChromatinNuclear laminaEpigeneticsHistoneHistone H3BiologyInduced pluripotent stem cellCellEmbryonic stem cellGeneticsDNANuclear proteinGeneTranscription factorPluripotent Stem Cells ResearchCellular Mechanics and Interactions3D Printing in Biomedical Research
Transient nuclear deformation primes epigenetic state and promotes cell reprogramming | Litcius