Cytokine storm in tuberculosis and IL-6 involvement
Funmilayo Grâce Boni, Insaf Hamdi, Liadrine Moukendza Koundi, Kanchan Shrestha, Jianping Xie
Abstract
Tuberculosis is probably the most seasoned illness of the humanity. Intricacies or subsequent death emerging from these infections are frequently connected with cytokine storm. Interleukin-6 (IL-6) plays a crucial role in the immune response to tuberculosis. Therefore, there is a need to research some new therapeutic approaches to block IL-6 signaling that are right now being applied to the M. tuberculosis. In this review, we investigate the implication of IL-6 in the context of tuberculosis research.
Topics & Concepts
TuberculosisBiologyCytokine stormImmunologyContext (archaeology)CytokineImmune systemDiseaseInfectious disease (medical specialty)Internal medicineMedicinePathologyCoronavirus disease 2019 (COVID-19)PaleontologyTuberculosis Research and EpidemiologyCytokine Signaling Pathways and InteractionsMycobacterium research and diagnosis