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The synthesis of diverse benzazepinoindoles <i>via</i> gold-catalyzed post-Ugi alkyne hydroarylation/Michael addition sequence

Chao Liu, Luc Van Meervelt, Vsevolod A. Peshkov, Erik V. Van der Eycken

2022Organic Chemistry Frontiers25 citationsDOIOpen Access PDF

Abstract

By combining an Ugi-4CR and a gold-catalyzed cascade cyclization, diverse benzazepinoindoles are assembled in a step-economical, chemo- and regioselectivity fashion.

Topics & Concepts

AlkyneChemistryMichael reactionSequence (biology)CatalysisCombinatorial chemistryOrganic chemistryStereochemistryBiochemistryCatalytic Alkyne ReactionsSynthetic Organic Chemistry MethodsCatalytic C–H Functionalization Methods
The synthesis of diverse benzazepinoindoles <i>via</i> gold-catalyzed post-Ugi alkyne hydroarylation/Michael addition sequence | Litcius