Novel insights on the molecular mechanism of action of the anti-angiogenic pyrazolyl-urea GeGe-3 by functional proteomics
Elva Morretta, Raffaella Belvedere, Antonello Petrella, Andrea Spallarossa, Federica Rapetti, Olga Bruno, Chiara Brullo, Maria Chiara Monti
Topics & Concepts
ChemistryInteractomeProteomicsMechanism of actionDocking (animal)CalreticulinIn silicoBiochemistryCombinatorial chemistryComputational biologyIn vitroBiologyGeneMedicineNursingEndoplasmic reticulumPeptidase Inhibition and AnalysisCell Adhesion Molecules ResearchUbiquitin and proteasome pathways