Bioenergetic Mechanisms Linking V˙O2 Kinetics and Exercise Tolerance
Richie P. Goulding, Harry B. Rossiter, Simon Marwood, Carrie Ferguson
Abstract
We hypothesize that the V˙O2 time constant (τV˙O2) determines exercise tolerance by defining the power output associated with a "critical threshold" of intramuscular metabolite accumulation (e.g., inorganic phosphate), above which muscle fatigue and work inefficiency are apparent. Thereafter, the V˙O2 "slow component" and its consequences (increased pulmonary, circulatory, and neuromuscular demands) determine performance limits.
Topics & Concepts
MetaboliteBioenergeticsChemistryCirculatory systemInefficiencyKineticsBiophysicsInternal medicineCardiologyMedicineBiochemistryBiologyMitochondrionPhysicsQuantum mechanicsEconomicsMicroeconomicsCardiovascular and exercise physiologySports Performance and TrainingMuscle activation and electromyography studies