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Synthesis and applications of fluorinated, polyfluoroalkyl- and polyfluoroaryl-substituted 1,2,3-triazoles

Frances E. Bugden, Joanna Westwood, H. E. N. Stone, Yingjian Xu, Mark D. Greenhalgh

2024Organic Chemistry Frontiers12 citationsDOIOpen Access PDF

Abstract

This review summarises methods to synthesise and apply fluorine- and polyfluoroalkyl/aryl-substituted 1,2,3-triazoles. Focus is devoted to recent examples and those where the properties of both the 1,2,3-triazole and fluorine groups are important.

Topics & Concepts

ChemistryFluorineArylCombinatorial chemistryTriazoleOrganic chemistryAlkylClick Chemistry and ApplicationsFluorine in Organic ChemistrySynthesis and Biological Evaluation