Litcius/Paper detail

Diabetic Nephropathy - a Review of Risk Factors, Progression, Mechanism, and Dietary Management

Vijayakumar Natesan, Sungjin Kim

2021Biomolecules & Therapeutics158 citationsDOIOpen Access PDF

Abstract

Type 2 diabetes mellitus (T2DM) leads to many health problems like diabetic nephropathy (DN). One of the key factors for chronic kidney disease and end-stage renal disease (ESRD) is T2DM. Extensive work is being done to delineate the pathogenesis of DN and to extend possible remedies. This review is intended to understand the nature of DN risk factors, progression, effects of glycemic levels, and stages of DN. We also explored the novel diagnostic and therapeutic approaches for DN such as gene therapy and stem cell treatments.

Topics & Concepts

Diabetic nephropathyMedicineDiseaseMechanism (biology)Diabetes mellitusGlycemicType 2 Diabetes MellitusKidney diseasePathogenesisBioinformaticsNephropathyIntensive care medicineInternal medicineEndocrinologyBiologyEpistemologyPhilosophyChronic Kidney Disease and DiabetesDiet and metabolism studiesLiver Disease Diagnosis and Treatment