Electrochemical chemoselective hydrogenation of 1,4-enediones with HFIP as the hydrogen donor: scalable access to 1,4-diketones
Haoran Li, Xue-Yang Guo, Ming‐Zhong Guo, Kui Liu, Li‐Rong Wen, Ming Li, Lin‐Bao Zhang
Abstract
A straightforward electrochemical protocol for efficient hydrogenation of unsaturated CC bonds has been reported in an undivided cell. A series of versatile 1,4-diketones are smoothly generated under metal-free and external-reductant-free electrolytic conditions. Moreover, the tolerance of various functional groups and decagram-scale experiments have shown the practicability and potential applications of this methodology. Moreover, a range of heterocyclic compounds were easily prepared through follow-up procedures of 1,4-diketones.
Topics & Concepts
ChemistryElectrochemistryCombinatorial chemistryHydrogen bondMetalMoleculeOrganic chemistryElectrodePhysical chemistryElectrocatalysts for Energy ConversionCO2 Reduction Techniques and CatalystsRadical Photochemical Reactions