Europium–tannic acid nanocomplexes devised for bone regeneration under oxidative or inflammatory environments
Daniel Fernández‐Villa, María Rosa Aguilar, Luís Rojo
Abstract
- and LPS-stimulated macrophages, respectively. Furthermore, the short-term treatment of osteoblasts with EuTA NCs was found to increase their alkaline phosphatase activity and their matrix mineralization capacity. Overall, this simple and tunable platform is a potential candidate to promote bone growth in complex environments by simultaneously targeting multiple pathophysiological mechanisms of disease.
Topics & Concepts
Tannic acidEuropiumAntioxidantRegeneration (biology)OsteopeniaChemistryMaterials scienceCell biologyBiochemistryMedicinePathologyOrganic chemistryBiologyOsteoporosisIonBone mineralBone Tissue Engineering MaterialsBone Metabolism and DiseasesBone health and osteoporosis research