Cytotoxicity comparison of Bio C Sealer against multiple root canal sealers.
Alba Tolosa-Monfà, Alma Veroni, Juan Blasi‐Cabus, Maria-Lluisa Ballester-Palacios, Esther Berástegui-Jimeno
Abstract
Background: The aim of this study was to compare the cytotoxicity of calcium silicate-based endodontic sealer, Bio-C® Sealer, with other calcium silicate-based sealers: BioRoot™ RCS, one silicon-based sealer combined with calcium silicate particles: GuttaFlow® Bioseal, one resin MTA-based root canal sealer: MTA Fillapex®, and an epoxy resin-based sealer: AH Plus®. Material and Methods: <0.05). The samples were examined under an inverted microscope to evaluate the effect of each sealer on fibroblast cell morphology. Results: <0.05). AH Plus® and MTA Fillapex® were not significantly different from one another; nor was BioRoot™ RCS from Bio-C® Sealer. Microscope examination found that fibroblasts in contact with GuttaFlow® Bioseal and Bio-C® Sealer presented the most similar aspects to the control group both in terms of number and shape. Conclusions: Biocompatibility, calcium silicate-based endodontic sealers, cytotoxicity, endodontic sealer.