Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras
Troy A. Bemis, James J. La Clair, Michael D. Burkart
Abstract
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Topics & Concepts
LinkerBottleneckProteolysisChemistryComputational biologyIn silicoRational designCombinatorial chemistryBiochemistryComputer scienceBiologyGeneticsEnzymeGeneOperating systemEmbedded systemProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments