Tryptophan metabolism regulates inflammatory macrophage polarization as a predictive factor for breast cancer immunotherapy
Linxuan Xue, Chao Wang, Y. Qian, Wenqiang Zhu, Lina Liu, Xiaohong Yang, Shuhua Zhang, Daya Luo
Topics & Concepts
Macrophage polarizationBreast cancerImmune systemTumor microenvironmentBiologyCancer researchImmunotherapyInternal medicineKynurenineIndoleamine 2,3-dioxygenaseCancerImmunologyTryptophanEndocrinologyMedicineMacrophageBiochemistryIn vitroAmino acidImmune cells in cancerTryptophan and brain disordersSingle-cell and spatial transcriptomics