Impact of PEGylation on an antibody-loaded nanoparticle-based drug delivery system for the treatment of inflammatory bowel disease
Neha Shrestha, Yining Xu, Julien R. C. Prévost, Fiona McCartney, David J. Brayden, Raphaël Frédérick, Ana Beloqui, Véronique Préat
Topics & Concepts
PLGAPEGylationDrug deliveryMucusIn vivoInflammatory bowel diseaseMonoclonal antibodyEx vivoTumor necrosis factor alphaProinflammatory cytokineMaterials scienceAntibodyPharmacologyPolyethylene glycolInflammationMedicineChemistryImmunologyNanoparticlePathologyBiologyNanotechnologyBiochemistryDiseaseBiotechnologyEcologyAdvanced Drug Delivery SystemsInfant Nutrition and HealthInflammatory Bowel Disease