Is a liver comparable to a liver? A comparison of different rat-derived S9-fractions with a biotechnological animal-free alternative in the Ames fluctuation assay
Julia Brendt, Sarah E. Crawford, Mirna Velki, Hongxia Xiao, Beat Thalmann, Henner Hollert, Andreas Schiwy
Topics & Concepts
S9 fractionAmes testFraction (chemistry)In vitroSalmonellaBiochemistryBiologyMetabolismMetabolic pathwayBioassayMicrosomeChemistryToxicologyChromatographyGeneticsBacteriaCarcinogens and Genotoxicity AssessmentComputational Drug Discovery MethodsPesticide Exposure and Toxicity