Litcius/Paper detail

Clinical trial design, biomarkers and end points in metabolic and alcohol-related liver disease

Luis Antonio Díaz, Maja Thiele, Alexandre Louvet, Brian P. Lee, Veeral Ajmera, Federica Tavaglione, Cynthia L. Hsu, Daniel Q. Huang, Elisa Pose, Ramón Bataller, Craig J. McClain, Jessica L. Mellinger, Monica A. Tincopa, Mack C. Mitchell, Vlad Ratziu, Mary E. Rinella, Shiv Kumar Sarin, Vijay H. Shah, Gyöngyi Szabó, Vincent Wai‐Sun Wong, Meena B. Bansal, Lorenzo Leggio, Patrick S. Kamath, Aleksander Krag, Arun J. Sanyal, Marco Arrese, Juan Pablo Arab, Quentin M. Anstee, Philippe Mathurin, Rohit Loomba

2025Nature Reviews Gastroenterology & Hepatology15 citationsDOI

Topics & Concepts

MedicineGeneralizability theoryClinical trialIntensive care medicineDiseaseLiver diseaseClinical study designPsychological interventionBioinformaticsClinical PracticeMEDLINESurrogate endpointEpidemiologyChronic liver diseaseDrug developmentRandomized controlled trialResearch designRisk assessmentObservational studyInclusion and exclusion criteriaClinical significanceAlcohol intakeInternal medicineLiver Disease Diagnosis and TreatmentAlcohol Consumption and Health EffectsLiver Disease and Transplantation