Palmitoylation licenses RIPK1 kinase activity and cytotoxicity in the TNF pathway
Na Zhang, Jianping Liu, Rui Guo, Lingjie Yan, Yuanxin Yang, Shilin Chen, Mengmeng Zhang, Bing Shan, Wanjin Li, Jinyang Gu, Daichao Xu
Topics & Concepts
BiologyCytotoxicityPalmitoylationTumor necrosis factor alphaCell biologyRIPK1KinaseCancer researchBiochemistryImmunologyEnzymeApoptosisProgrammed cell deathIn vitroCysteineNecroptosisCell death mechanisms and regulationDrug-Induced Hepatotoxicity and ProtectionNF-κB Signaling Pathways