A <i>Lupinus angustifolius</i> protein hydrolysate exerts hypocholesterolemic effects in Western diet-fed ApoE<sup>−/−</sup> mice through the modulation of LDLR and PCSK9 pathways
Guillermo Santos‐Sánchez, Ivan Cruz‐Chamorro, Carlotta Bollati, Martina Bartolomei, Justo Pedroche, Francisco Millán, María C. Millán-Linares, Anna Laura Capriotti, Andrea Cerrato, Aldo Laganà, Anna Arnoldi, Antonio Carrillo‐Vico, Carmen Lammi
Abstract
Lupin protein hydrolysates (LPHs) are gaining attention in the food and nutraceutical industries due to their several beneficial health effects.
Topics & Concepts
LDL receptorPCSK9HydrolysateCholesterolChemistrySignal transductionPhosphorylationTranscription factorReceptorSterol regulatory element-binding proteinTriglycerideBiochemistryInternal medicineEndocrinologyBiologyLipoproteinSterolGeneHydrolysisMedicineBotanical Research and ChemistryLipid metabolism and biosynthesisBiochemical Analysis and Sensing Techniques