Poria cocos polysaccharides attenuated ox-LDL-induced inflammation and oxidative stress via ERK activated Nrf2/HO-1 signaling pathway and inhibited foam cell formation in VSMCs
Jinmeng Zhao, Xinyi Niu, Jinjin Yu, Xin Xiao, Wenqi Li, Wenqi Li, Lulu Zang, Zhen Hu, Siu‐Po Ip, Weifeng Li, Weifeng Li
Topics & Concepts
Oxidative stressMAPK/ERK pathwayInflammationReactive oxygen speciesChemistrySignal transductionHeme oxygenaseCell biologyFoam cellOxidative phosphorylationIntracellularVascular smooth muscleBiochemistryPharmacologyBiologyHemeMacrophageImmunologyEndocrinologyEnzymeIn vitroSmooth muscleAtherosclerosis and Cardiovascular DiseasesNeutrophil, Myeloperoxidase and Oxidative MechanismsMicrobial metabolism and enzyme function