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High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells

Hui Kwon Kim, Sungtae Lee, Younggwang Kim, Jinman Park, Seonwoo Min, Jae Woo Choi, Tony P. Huang, Sungroh Yoon, David R. Liu, Seokjoong Kim, Seokjoong Kim, Seokjoong Kim

2020Nature Biomedical Engineering144 citationsDOIOpen Access PDF

Topics & Concepts

Cas9CRISPRGenome editingBiologyComputational biologyGeneticsGeneCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsCytomegalovirus and herpesvirus research
High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells | Litcius