Thio- and selenosemicarbazones as antiprotozoal agents against <i>Trypanosoma cruzi</i> and <i>Trichomonas vaginalis</i>
Alexandra Ibáñez‐Escribano, Cristina Fonseca‐Berzal, Mónica Martínez-Montiel, Manuel Álvarez-Márquez, María Gómez-Núñez, Manuel Lacueva-Arnedo, Teresa Espinosa-Buitrago, Tania Martín‐Pérez, José Antonio Escario, Penélope Merino‐Montiel, Sara Montiel‐Smith, Alicia Gómez‐Barrio, Óscar López, José G. Fernández‐Bolaños
Abstract
=11.10 and 11.02 µM, respectively). Hydrogenosome membrane potential and structural changes were analysed to get more insight into the trichomonacidal mechanism.
Topics & Concepts
AntiprotozoalTrypanosoma cruziTrichomonas vaginalisBenznidazoleIC50Vero cellChemistryStereochemistryCytotoxicityChagas diseaseStrain (injury)MicrobiologyIn vitroBiologyBiochemistryVirologyWorld Wide WebParasite hostingAnatomyComputer scienceResearch on Leishmaniasis StudiesTrypanosoma species research and implicationsSynthesis and Biological Evaluation