Bidirectional Interactions between Arboviruses and the Bacterial and Viral Microbiota in Aedes aegypti and Culex quinquefasciatus
Chenyan Shi, Leen Beller, Lanjiao Wang, Ana Rosales Rosas, Lander De Coninck, Lyza Héry, Laurence Mousson, Nonito Pagès, Jeroen Raes, Leen Delang, Anubis Vega-Rúa, Anna‐Bella Failloux, Jelle Matthijnssens
Abstract
In this study, we first utilized the single mosquito microbiome analysis, demonstrating a complex three-way interaction among arboviruses, resident microbiota, and the host, which is distinct for different arbovirus–mosquito combinations. Some of the previously described “core virus” increased in the mosquitos receiving viral blood meal, like Guadeloupe mosquito virus and Guadeloupe Culex tymo-like virus, suggesting their potential roles in ZIKV and WNV infection.
Topics & Concepts
BiologyCulex quinquefasciatusAedes aegyptiArbovirusZika virusChikungunyaCulexAedesVirologyVector (molecular biology)Dengue feverBlood mealHuman viromeFlavivirusVirusMicrobiologyZoologyEcologyMetagenomicsLarvaGeneticsRecombinant DNAGeneInsect symbiosis and bacterial influencesMosquito-borne diseases and controlInvertebrate Immune Response Mechanisms