Development of a β-cyclodextrin-modified gold nanoparticle-assisted electromembrane extraction method followed by capillary electrophoresis for methadone determination in plasma
Mir Saleh Hoseininezhad-Namin, Síbel A. Özkan, Elaheh Rahimpour, Abolghasem Jouyban
Abstract
Gold nanoparticles (AuNPs) modified with β-cyclodextrin (β-CD) were used to assist with electromembrane extraction (EME) and were coupled with capillary electrophoresis (CE) for the extraction and measurement of methadone from plasma samples.
Topics & Concepts
ChromatographyDetection limitCapillary electrophoresisExtraction (chemistry)Colloidal goldAnalyteChemistryMembraneCyclodextrinNanoparticleMaterials scienceAnalytical Chemistry (journal)NanotechnologyBiochemistryAnalytical chemistry methods developmentElectrochemical sensors and biosensorsMicrofluidic and Capillary Electrophoresis Applications