<i>In vivo</i> imaging of the human cornea with high-speed and high-resolution Fourier-domain full-field optical coherence tomography.
Egidijus Auksorius, Dawid Borycki, Patrycjusz Stremplewski, Kamil Liżewski, Sławomir Tomczewski, Paulina Niedźwiedziuk, Bartosz L. Sikorski, Maciej Wojtkowski
Abstract
with FD-FF-OCT that can acquire a single 3D volume with a voxel rate of 7.8 GHz. The spatial coherence of the laser source was suppressed to prevent it from focusing on a spot on the retina, and therefore, exceeding the maximum permissible exposure (MPE). The inherently volumetric nature of FD-FF-OCT data enabled flattening of curved corneal layers. The acquired FD-FF-OCT images revealed corneal cellular structures, such as epithelium, stroma and endothelium, as well as subbasal and mid-stromal nerves.
Topics & Concepts
Optical coherence tomographyOpticsCorneaPreclinical imagingFourier domainMaterials scienceFlatteningBiomedical engineeringPhysicsIn vivoMedicineBiotechnologyBiologyComposite materialOptical Coherence Tomography ApplicationsCorneal surgery and disordersGlaucoma and retinal disorders