Skeletal Ring Contractions via I(I)/I(III) Catalysis: Stereoselective Synthesis of <i>cis</i>-α,α-Difluorocyclopropanes
Keith Livingstone, Kathrin Siebold, Stephanie Meyer, Víctor Martín‐Heras, Constantin G. Daniliuc, Ryan Gilmour
Abstract
→ π* interactions that manifest themselves in this conformation (e.g., collagen), it is envisaged that the title motif will find application in focused molecular design.
Topics & Concepts
StereoselectivityChemistryMoietyOrganocatalysisStereochemistryAlkeneCatalysisRing (chemistry)Brønsted–Lowry acid–base theoryCombinatorial chemistryEnantioselective synthesisOrganic chemistryFluorine in Organic ChemistryCyclopropane Reaction MechanismsCarbon dioxide utilization in catalysis