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NHC-catalyzed formal [3 + 3] annulations of δ-acetoxy allenoates for the synthesis of 4<i>H</i>-pyran derivatives

Bai Shi, F.N. Jin, Qi Lv, Xinrong Zhou, Zhixiao Liao, Chenxia Yu, Kai Zhang, Changsheng Yao

2023Organic & Biomolecular Chemistry12 citationsDOI

Abstract

Herein, an N-heterocyclic carbene (NHC) catalyzed formal [3 + 3] annulation of δ-acetoxy allenoates with 1C,3O-bisnucleophiles for the construction of 4 H -(fused)pyrans has been developed.

Topics & Concepts

PyranChemistryCatalysisFormal synthesisStereochemistryOrganic chemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsSynthetic Organic Chemistry Methods
NHC-catalyzed formal [3 + 3] annulations of δ-acetoxy allenoates for the synthesis of 4<i>H</i>-pyran derivatives | Litcius