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Remodeling ceramide homeostasis promotes functional maturation of human pluripotent stem cell-derived β cells

Huijuan Hua, Yaqi Wang, Xiaofeng Wang, Shusen Wang, Yunlu Zhou, Yinan Liu, Zhen Liang, Huixia Ren, Sufang Lu, Shuangshuang Wu, Yong Jiang, Yue Pu, Zheng Xiang, Chao Tang, Zhongyang Shen, Cheng Li, Yuanyuan Du, Hongkui Deng

2024Cell stem cell20 citationsDOI

Topics & Concepts

BiologyInduced pluripotent stem cellCell biologyStem cellTranscriptomeSphingolipidCeramideGlucose homeostasisCellEmbryonic stem cellInsulinBiochemistryEndocrinologyApoptosisGene expressionInsulin resistanceGenePancreatic function and diabetesZebrafish Biomedical Research ApplicationsImmune Cell Function and Interaction
Remodeling ceramide homeostasis promotes functional maturation of human pluripotent stem cell-derived β cells | Litcius