The PPARγ-dependent effect of flavonoid luteolin against damage induced by the chemotherapeutic irinotecan in human intestinal cells
Thaise Boeing, Silvia Speca, Priscila de Souza, Anthony Martin Mena, Benjamin Bertin, Pierre Desreumax, Luísa Mota da Silva, Sérgio Faloni de Andrade, Laurent Dubuqoy
Topics & Concepts
LuteolinIrinotecanOxidative stressPharmacologyDownregulation and upregulationCamptothecinInflammationChemistryPeroxisome proliferator-activated receptorCancer researchFlavonoidBiologyColorectal cancerMedicineCancerImmunologyReceptorBiochemistryAntioxidantInternal medicineGeneCancer therapeutics and mechanismsNF-κB Signaling PathwaysGenomics, phytochemicals, and oxidative stress