Synthesis, biological assessment, and in silico binding mode interaction analyses and DFT studies of biphenylsulfonamide-based potent MMP-2 inhibitors effective against chronic myeloid leukemia
Sandip Kumar Baidya, Tarun Patel, Ambati Himaja, Suvankar Banerjee, Sanjib Das, Balaram Ghosh, Tarun Jha, Nilanjan Adhikari
Topics & Concepts
ChemistryIn silicoMyeloid leukemiaMatrix metalloproteinaseComputational biologyPharmacologyCancer researchBiochemistryGeneBiologyMedicineFerrocene Chemistry and ApplicationsProtease and Inhibitor MechanismsPeptidase Inhibition and Analysis