Pyoverdine Inhibitors and Gallium Nitrate Synergistically Affect Pseudomonas aeruginosa
Donghoon Kang, Alexey V. Revtovich, Alex Deyanov, Natalia V. Kirienko
Abstract
P. aeruginosa is one of the most common causative agents for ventilator-associated pneumonia and nosocomial bacteremia and is a leading cause of death in patients with cystic fibrosis. Pandrug-resistant strains of P. aeruginosa are increasingly identified in clinical samples and show resistance to virtually all major classes of antibiotics, including aminoglycosides, cephalosporins, and carbapenems.
Topics & Concepts
PyoverdinePseudomonas aeruginosaMicrobiologyBiofilmPathogenCystic fibrosisAntibioticsPyocyaninBiologyGalliumPneumoniaVirulenceBacteriaChemistryMedicineQuorum sensingBiochemistryGeneInternal medicineOrganic chemistryGeneticsAntibiotic Resistance in BacteriaBacterial biofilms and quorum sensingAntimicrobial Resistance in Staphylococcus