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Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution

Zhaoning Wang, Miao Cui, Akansha M. Shah, Wei Tan, Ning Liu, Rhonda Bassel‐Duby, Eric N. Olson

2021Cell Reports17 citationsDOIOpen Access PDF

Abstract

(Cell Reports 33, 108472-1–108472-17.e1–e6; December 8, 2020)In the originally published supplemental information of this article, incorrect immunofluorescent images were inserted into Figure S6F. The original figure appears here, and the corrected figure appears here and with the article online. The correction does not impact the interpretation of the data or the conclusion of the paper.View Large Image Figure ViewerDownload Hi-res image Download (PPT) (Cell Reports 33, 108472-1–108472-17.e1–e6; December 8, 2020) In the originally published supplemental information of this article, incorrect immunofluorescent images were inserted into Figure S6F. The original figure appears here, and the corrected figure appears here and with the article online. The correction does not impact the interpretation of the data or the conclusion of the paper. Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell ResolutionWang et al.Cell ReportsDecember 08, 2020In BriefUsing single-cell sequencing technologies, Wang et al. present single-cell databases of gene expression and open chromatin landscapes of heart cells during murine neonatal heart regeneration. Comparing the injury responses of regenerative and non-regenerative hearts reveals gene regulatory networks, cellular crosstalk, and secreted factors involved in the regeneration process. Full-Text PDF Open Access

Topics & Concepts

BiologyRegeneration (biology)Cell typeEmbryonic stem cellCellCrosstalkGeneGene expressionChromatinCell biologyGene regulatory networkSingle-cell analysisComputational biologyGeneticsPhysicsOpticsCongenital heart defects researchCongenital Heart Disease StudiesMechanical Circulatory Support Devices
Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution | Litcius