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Advancements in microwave ablation for tumor treatment and future directions

Fangying Dong, Yijie Wu, Weiwei Li, Xiaoping Li, Jing Zhou, Bin Wang, Minjie Chen

2025iScience19 citationsDOIOpen Access PDF

Abstract

Microwave ablation (MWA) is a minimally invasive treatment that uses thermal energy to target and destroy tumors. Compared to other ablation methods, such as radiofrequency ablation (RFA), MWA operates at higher frequencies, allowing for faster ablation and larger treatment areas. In addition to its direct tumor-destroying effects, MWA has been shown to activate immune responses, contributing to long-term antitumor effects. MWA can also be combined with surgery, chemotherapy, and immunotherapy to enhance treatment outcomes. This review examines the current research on MWA's technical innovations, clinical applications, and its potential in improving cancer treatment efficacy.

Topics & Concepts

Microwave ablationTumor ablationMicrowaveNanotechnologyAblationEngineering physicsMaterials scienceEngineeringTelecommunicationsAerospace engineeringRenal cell carcinoma treatmentHepatocellular Carcinoma Treatment and PrognosisRadiation Therapy and Dosimetry
Advancements in microwave ablation for tumor treatment and future directions | Litcius