Litcius/Paper detail

Direct coupling of inert C–H bonds in NHC organocatalysis

Hongling Wang, SU Fen, Yanyan Wang, Xingxing Wu, Yonggui Robin

2023Organic Chemistry Frontiers14 citationsDOIOpen Access PDF

Abstract

Direct coupling of inert C–H bonds by NHCs offers efficient routes for the synthesis of functional molecules. Consequently, this highlight presents the latest advancements in NHC-catalyzed latent C–H functionalization involving the ET/PT pathways and HAT pathway.

Topics & Concepts

ChemistryInertSurface modificationOrganocatalysisCombinatorial chemistryCoupling (piping)CatalysisMoleculeOrganic chemistryEnantioselective synthesisPhysical chemistryMechanical engineeringEngineeringN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization Methods