Limited Treatment Options for Diabetic Wounds: Barriers to Clinical Translation Despite Therapeutic Success in Murine Models
May Barakat, Luisa A. DiPietro, Lin Chen
Abstract
As research continues to decipher deficient healing in diabetes, new approaches and considerations are required to ensure that these discoveries can become translational, clinically usable therapies. Clinical progress requires the development of new, more accurate models of the human disease state, multifaceted investigations that address multiple critical components in wound repair, and more innovative research strategies that harness both the existing knowledge and the potential of new advances across disciplines.
Topics & Concepts
MedicineTranslation (biology)Intensive care medicineBioinformaticsBiologyBiochemistryGeneMessenger RNAWound Healing and TreatmentsMesenchymal stem cell researchDiabetic Foot Ulcer Assessment and Management