Dissolving Microneedles with Spatiotemporally controlled pulsatile release Nanosystem for Synergistic Chemo-photothermal Therapy of Melanoma
Wanbing Qin, Guilan Quan, Ying Sun, Minglong Chen, Peipei Yang, Disang Feng, Ting Wen, Xinyu Hu, Xin Pan, Chuanbin Wu
Abstract
Herein, we developed a DMN system with a unique spatiotemporally controlled pulsatile release feature that provides a user-friendly and low-toxicity treatment route for patients who need long-term and repeat treatments.
Topics & Concepts
Photothermal therapyPulsatile flowNanotechnologyMaterials scienceDissolutionBiomedical engineeringMelanomaChemistryMedicineCancer researchInternal medicinePhysical chemistryAdvancements in Transdermal Drug DeliveryGold and Silver Nanoparticles Synthesis and ApplicationsSpectroscopy Techniques in Biomedical and Chemical Research