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Detection of low-frequency DNA variants by targeted sequencing of the Watson and Crick strands

Joshua D. Cohen, Christopher Douville, Jonathan C. Dudley, Brian J. Mog, Maria Popoli, Janine Ptak, Lisa Dobbyn, Natalie Silliman, Joy Schaefer, Jeanne Tie, Peter Gibbs, Cristian Tomasetti, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein

2021Nature Biotechnology91 citationsDOIOpen Access PDF

Topics & Concepts

Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic AcidDNAComputational biologyGeneticsDNA sequencingBiologyBase pairBacteriophages and microbial interactionsCancer Genomics and DiagnosticsAdvanced biosensing and bioanalysis techniques
Detection of low-frequency DNA variants by targeted sequencing of the Watson and Crick strands | Litcius