Epigenetic regulation of the DNMT1/MT1G/KLF4/CA9 axis synergises the anticancer effects of sorafenib in hepatocellular carcinoma
Tianzi Wei, Risheng Lin, Xing Fu, Yi Lü, Weiwen Zhang, Zhengxuan Li, Jian Zhang, Hao Wang
Topics & Concepts
SorafenibHepatocellular carcinomaCancer researchDNMT1KLF4EpigeneticsDownregulation and upregulationPharmacologyMedicineMethyltransferaseChemistryTranscription factorMethylationBiochemistryDNASOX2GeneKruppel-like factors researchMicroRNA in disease regulationEpigenetics and DNA Methylation