Functional roles of antisense enhancer RNA for promoting prostate cancer progression
Chun‐Wu Pan, Simeng Wen, Lei Chen, Yulei Wei, Yuanjie Niu, Yu Zhao
Abstract
The findings indicated that antisense eRNA was a functional RNA and may be a novel target that when suppressed improved prostate cancer therapy and diagnosis. New chromatin interaction among enhancer, promoter and gene-ending region might provide new insight into the spatiotemporal mechanism of the gene transcription and acting of bi-directional eRNAs.
Topics & Concepts
Antisense RNAEnhancerRNASense (electronics)BiologyDNA methylationMolecular biologyNon-coding RNAMethylationGeneLong non-coding RNACancer researchProstate cancerGene expressionCancerChemistryGeneticsPhysical chemistryCancer-related molecular mechanisms researchRNA Research and SplicingRNA modifications and cancer