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The Potential of Thiazole Derivatives as Antimicrobial Agents

Shabnam Thakur, Rupali Sharma, Rakesh Kumar Yadav, Satish Sardana

202215 citationsDOIOpen Access PDF

Abstract

A transnational concern for the healthy development of human beings is antimicrobial resistance (AMR). The rising rates of microbial resistance present a serious issue for the development of human life and hence it is essential to find and create newer antimicrobial drugs with unique modes of action. One approach used these days to solving this challenge is the use of heterocyclics to create hybrid compounds by fusing two or more bioactive heterocyclic moieties into a single molecular platform. This study discusses the many hybrid approaches that have been used to produce possible novel antimicrobial medicines that are both safe and effective. The landscaping of heterocycles such as thiazole derivatives is covered in the current review paper. In this paper, all the extensive approaches of heterocyclic composites, primarily thiazole derivatives, exhibit vibrant biological activity. The purpose of this work is to support methods that may be used to create various thiazole derivatives and their biological activity. This paper will offer great recommendations for potential medicine designs in the future.

Topics & Concepts

ThiazoleAntimicrobialBiochemical engineeringCombinatorial chemistryHuman lifeAntibiotic resistanceRisk analysis (engineering)Computer scienceBiotechnologyNanotechnologyChemistryEngineeringBusinessBiologyMaterials scienceOrganic chemistryAntibioticsBiochemistryTheologyHumanityPhilosophySynthesis and biological activityClick Chemistry and ApplicationsMulticomponent Synthesis of Heterocycles
The Potential of Thiazole Derivatives as Antimicrobial Agents | Litcius