Salt-stabilized alkylzinc pivalates: versatile reagents for cobalt-catalyzed selective 1,2-dialkylation
Jie Lin, Kaixin Chen, Jixin Wang, Jiawei Guo, Siheng Dai, Ying Hu, Jie Li
Abstract
cross-couplings. Furthermore, facile modifications of bioactive molecules and fluorinated products demonstrate the synthetical utility of our salt-stabilized alkylzinc reagents and cobalt-catalyzed alkyldifluoroalkylation protocol.
Topics & Concepts
ReagentCobaltCatalysisSalt (chemistry)ChemistryCombinatorial chemistryOrganic chemistryFluorine in Organic ChemistryCatalytic C–H Functionalization MethodsAsymmetric Synthesis and Catalysis