<i>In Silico</i>, <i>In Vitro</i>, and <i>In Vivo</i> Evaluation of the Developmental Toxicity, Estrogenic Activity, and Mutagenicity of Four Natural Phenolic Flavonoids at Low Exposure Levels
Xinwen Zhang, Changqing Wu
Abstract
pmol/plate. The findings showed nonmonotonic dose responses for the chemicals.
Topics & Concepts
ApigeninLuteolinGenisteinQuercetinFlavonoidToxicityPharmacologyIn vivoNutraceuticalChemistryPhytoestrogensKaempferolBiologyTraditional medicineBiochemistryAntioxidantMedicineBiotechnologyEstrogenGeneticsOrganic chemistryEndocrinologyPhytochemicals and Antioxidant ActivitiesComputational Drug Discovery MethodsPhytoestrogen effects and research