Photoinduced Cross-Coupling of Aryl Iodides with Alkenes
Yuliang Liu, Haoyu Li, Shunsuke Chiba
Abstract
A protocol for photoinduced cross-coupling of aryl iodides having polar π-functional groups or elongated π-conjugation with alkenes has been developed. The radical cascade mechanism involving generation of aryl radicals via C-I bond homolysis of photoexcited aryl iodides and their subsequent addition to alkenes is proposed. The method enables iodide-selective cross-coupling over other halogen leaving groups with functional group compatibility on both arene and alkene motifs.
Topics & Concepts
ChemistryArylHomolysisAlkeneRadicalIodidePhotochemistryAryl radicalCoupling reactionFunctional groupHalogenCascadeOrganic chemistryCatalysisAlkylPolymerChromatographyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques