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NRG1 regulates Fra-1 transcription and metastasis of triple-negative breast cancer cells via the c-Myc ubiquitination as manipulated by ERK1/2-mediated Fbxw7 phosphorylation

Le Shu, Ao Chen, Linrui Li, Lun Yao, Yiduo He, Jianbo Xu, Wei Gu, Qiang Li, Kun Wang, Tongcun Zhang, Guoquan Liu

2022Oncogene27 citationsDOI

Topics & Concepts

Cancer researchTriple-negative breast cancerTranscription factorBiologyUbiquitin ligaseMetastasisBreast cancerOncogeneGene knockdownEpidermal growth factor receptorCell cycleUbiquitinCancerCell cultureGeneticsGeneHER2/EGFR in Cancer ResearchCytokine Signaling Pathways and InteractionsUbiquitin and proteasome pathways
NRG1 regulates Fra-1 transcription and metastasis of triple-negative breast cancer cells via the c-Myc ubiquitination as manipulated by ERK1/2-mediated Fbxw7 phosphorylation | Litcius