Walking metals: catalytic difunctionalization of alkenes at nonclassical sites
Roshan K. Dhungana, Rishi R. Sapkota, Doleshwar Niroula, Ramesh Giri
Abstract
) carbon sites with a variety of coupling partners. These reactions have enabled engineering of complex molecular frameworks with the generation of new carbon-carbon (C-C)/C-C, C-C/C-heteroatom (halogens, O, N, B) and C-B/C-B bonds. The development of these unique transformations is also presented with mechanistic hypotheses and experimental evidences put forward by researchers. Judged by the number of reports emerging recently, it is now strikingly evident that the field of alkene difunctionalization by metal migration has begun to gain momentum, which holds a great future prospect to develop into a synthetic method of enormous potential.
Topics & Concepts
CatalysisChemistryHeavy metalsCombinatorial chemistryEnvironmental chemistryOrganic chemistryCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and CatalysisAsymmetric Synthesis and Catalysis